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Volume 13 · Number 1 · Pages 147–149
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Function vs. Structure: The Immune System as a Case in Point

Jorge Mpodozis

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Abstract

Open peer commentary on the article “The Epigenetic Immune Network” by Nelson Monteiro Vaz & Luiz Antônio Botelho Andrade. Upshot: Functional approaches to systems, while of heuristic value in many cases, may lead to a neglect of some fundamental aspects of systemic phenomenology. The adoption of an alternative structural/mechanistic approach can be very enlightening to unveil, and effective to solve, the conceptual and heuristic limitations resulting from the adoption of the functional approach. The epistemic history of immunology, as described in the target article, offers compelling evidences of this situation.

Citation

Mpodozis J. (2017) Function vs. Structure: The immune system as a case in point. Constructivist Foundations 13(1): 147–149. http://constructivist.info/13/1/147

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References

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Costa R. A., Ruiz-de-Souza V., Azevedo Jr. G. M., Gava E., Kitten G. T., Vaz N. M. & Carvalho C. R. (2011) Indirect effects of oral tolerance improve wound healing in skin. Wound Repair and Regeneration 19(4): 487–497. ▸︎ Google︎ Scholar
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Maturana H. R., Mpodozis J. & Letelier J. C. (1995) Brain, language and the origin of human mental functions. Biological Research 28(1): 15–26. ▸︎ Google︎ Scholar
Vaz N., Faria A. M. C., Verdolin B. A. & Carvalho C. R. (1997) Immaturity, ageing and oral tolerance. Scandinavian Journal of Immunology 46(3): 225–229. ▸︎ Google︎ Scholar
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