Function vs. Structure: The Immune System as a Case in Point
Jorge Mpodozis
Log in download the full text in PDF
> Citation
> Similar
> References
> Add Comment
Abstract
Open peer commentary on the article “The Epigenetic Immune Network” by Nelson Monteiro Vaz & Luiz Antônio Botelho Andrade. Upshot: Functional approaches to systems, while of heuristic value in many cases, may lead to a neglect of some fundamental aspects of systemic phenomenology. The adoption of an alternative structural/mechanistic approach can be very enlightening to unveil, and effective to solve, the conceptual and heuristic limitations resulting from the adoption of the functional approach. The epistemic history of immunology, as described in the target article, offers compelling evidences of this situation.
Citation
Mpodozis J. (2017) Function vs. Structure: The immune system as a case in point. Constructivist Foundations 13(1): 147–149. http://constructivist.info/13/1/147
Export article citation data:
Plain Text ·
BibTex ·
EndNote ·
Reference Manager (RIS)
References
Carvalho C. R., Lenzi H. L., Correa-Oliveira R. & Vaz N. M. (2002) Indirect effects of oral tolerance to ovalbumin interfere with the immune responses triggered by Schistosoma mansoni eggs. Brazilian Journal of Medical and Biological Research 35(10): 1195–1199.
▸︎ Google︎ Scholar
Costa R. A., Ruiz-de-Souza V., Azevedo Jr. G. M., Gava E., Kitten G. T., Vaz N. M. & Carvalho C. R. (2011) Indirect effects of oral tolerance improve wound healing in skin. Wound Repair and Regeneration 19(4): 487–497.
▸︎ Google︎ Scholar
Haury M., Sundblad A., Grandien A., Barreau C., Coutinho A. & Nobrega A. (1997) The repertoire of serum IgM in normal mice is largely independent of external antigenic contact. European Journal of Immunology 27(6): 1557–1563.
▸︎ Google︎ Scholar
Verdolin B. A., Ficker S. M., Faria A. M. C., Vaz N. M. & Carvalho C. R. (2001) Stabilization of serum antibody responses triggered by initial mucosal contact with the antigen independently of oral tolerance induction. Brazilian Journal of Medical and Biological Research 34(2): 211–219.
▸︎ Google︎ Scholar
Comments: 0
To stay informed about comments to this publication and post comments yourself, please log in first.